Functional Medicine
Approach To
Chronic Migraine

A migraine can cause severe, often throbbing pain usually on just one side of the head. It is often accompanied by nausea, vomiting, sensitivity to light and sound, and worsening of symptoms with activity. Although a single episode of migraine lasts 4 to 72 hours those with Chronic Migraine experience a minimum of 8 migraine days per month and at least 15 days per month of headache of any kind.

Warning Symptoms Of Chronic Migraine

Warning symptoms known as “aura” may occur before or with the headache. These can include flashes of light, blind spots, or tingling on one side of the face or in your arm or leg. Migraine can mimic the symptoms of stroke, and leave a stroke in its wake, or be associated with a seizure. More complex presentations of migraine may not have headache as a prominent symptom. These have been called “Late Life Migrainous Accompaniment,” but despite their name they can affect those as young as 40 years of age. More modern terminology has been adopted in the classification system known as The International Headache Society ICHD-3 Beta. Vertigo (a false sense of motion), slurred speech, ringing in the ears, double vision, staggering gait, and loss of consciousness can be associated with migraine with brainstem aura.

Genetics & Environmental Factors Play Role In Migraine

A combination of genetics and environmental factors appear to play a role in migraine. Migraine may be caused by changes in the brainstem and its interactions with the trigeminal nerve, a major pain pathway. Imbalances in brain chemicals – including serotonin, which helps regulate pain in your nervous system – also may be involved. Serotonin levels drop during migraine attacks. This may cause your trigeminal nerve to release substances called neuropeptides, which travel to your brain’s outer covering (meninges). The result is migraine pain. Other neurotransmitters play a role in the pain of migraine, including calcitonin gene-related peptide (CGRP).

What Factors Trigger Your Migraine?

Environmental factors that have been associated with migraine include imbalances in hormones, food sensitivities, chemicals, alcohol, stress, changes in the wake-sleep pattern, physical factors, and changes of weather or barometric pressure. When using a functional medicine approach it is important to recognize the role of the gut. This includes a role for the microbiome (including nitrate-reducing bacteria in the mouth) because migraine sufferers have a different mix of gut bacteria that can make them more sensitive to certain foods, for example. This, in turn, activates the gut-associated immune system and alters gut permeability (“leaky gut”). Interestingly, low levels of serotonin in the gut, where most serotonin in the body is produced (by gut bacteria), appear to be linked to migraine.

We Discover The Root Cases For Your Migraine

Since our Springfield functional medicine doctor evaluates the causes of chronic illness the functional medicine approach is ideal for addressing migraine at its roots. To accomplish this goal, it uses the Functional Medicine operating system. This consists of the Functional Medicine Timeline, The Functional Medicine Matrix, and the Therapeutic Lifestyle Factors (Sleep & Relaxation, Movement & Exercise, Nutrition, Stress, and Relationships). Functional Medicine Matrix, based on a scientific framework known as “systems biology,” allows the practitioner to evaluate imbalances at the cellular level. This helps sort out why the disease has occurred in the first place. By understanding each of these imbalances the person with migraine is empowered to make changes to correct them. Each part of the Matrix is called a “node,” and there are 7 nodes on the Functional Medicine Matrix. You can read about them here: Assimilation, Defense & Repair, Energy, Biotransformation & Elimination, Structural Integrity, Transport, and Communication.

Understand The Seven “Nodes” on the Functional Medicine Matrix


Please click to learn about the Assimilation node of the Functional Medicine Matrix. Assimilation refers to digestion and absorption of nutrients in the gut, as well as the health, diversity, and balance of the microbes that inhabit the digestive tract.


Please click to learn about the Biotransformation & Elimination node of the Functional Medicine Matrix.Biotransformation & Elimination refers to the way in which the body handles products of metabolism, toxic elements, drugs, and other chemicals, and eliminates waste through the urine, stool, and sweat.


Please click to learn about the Communication node of the Functional Medicine Matrix. Communication refers to hormones, neurotransmitters (the chemicals nerve cells use to communicate with one another), and inflammatory mediators called “cytokines.”

Defense & Repair

Please click to learn about the Defense & Repair node of the Functional Medicine Matrix.Defense & Repair refers to chronic inflammation, how different parts of the body influence the immune system, and the factors that lead to a breakdown in the normal role of the immune system.


Please click to learn about the Energy node of the Functional Medicine Matrix. Energy refers to the way that every cell in your body creates the fuel that it needs to carry out normal biological functions.

Structural Integrity & Transport

Please click to learn about the Structural Integrity & Transport nodes of the Functional Medicine Matrix. These refer to two critical and over-lapping functions in the systems that govern how the body works.

Schedule Free

Your first step is to schedule a free 15-minute telephone consultation with Callie Maggard, Brain Tune Up! Program Coordinator. Please select the time you can be reached by telephone and complete the form afterwards. These steps are critical! Because of the high volume of interest, we are unable to answer your calls or questions until you have scheduled through this process and completed the intake form.

telemedicine neurology and functional medicine
Program Coordinator: Callie Maggard“Thank you for your interest in our program. I look forward to speaking with you about your health conditions and how our program could potentially help change the trajectory of your health.”

My program accepts out-of-state patients. Brain Tune Up! is a 5-8 month program. In order to be accepted into my program my team and I have to see you for the two-day initial neurological evaluation in-person, but we then can customize the rest of the program in a virtual setting for patients who are traveling from far distances. This will be explained when you schedule a telephone consultation.